diff --git a/eng/Subsets.props b/eng/Subsets.props
index 6f2bfd8be05e24..024e7ce3564fe6 100644
--- a/eng/Subsets.props
+++ b/eng/Subsets.props
@@ -509,9 +509,9 @@
       <ItemGroup Condition="'$(PgoInstrument)' != 'true'">
         <SharedFrameworkProjectToBuild Condition="'$(BuildMonoAOTCrossCompilerOnly)' != 'true'" Include="$(InstallerProjectRoot)pkg\sfx\Microsoft.NETCore.App\Microsoft.NETCore.App.Ref.sfxproj" />
       </ItemGroup>
-      <ItemGroup Condition="'$(BuildNativeAOTRuntimePack)' != 'true'">
+      <ItemGroup Condition="'$(BuildNativeAOTRuntimePack)' != 'true' and '$(PgoInstrument)' != 'true'">
         <SharedFrameworkProjectToBuild Condition="'$(RuntimeFlavor)' == '$(PrimaryRuntimeFlavor)'" Include="$(InstallerProjectRoot)pkg\sfx\Microsoft.NETCore.App\Microsoft.NETCore.App.Host.sfxproj" />
-        <SharedFrameworkProjectToBuild Condition="'$(RuntimeFlavor)' != 'Mono' and '$(PgoInstrument)' != 'true'" Include="$(InstallerProjectRoot)pkg\sfx\Microsoft.NETCore.App\Microsoft.NETCore.App.Crossgen2.sfxproj" />
+        <SharedFrameworkProjectToBuild Condition="'$(RuntimeFlavor)' != 'Mono'" Include="$(InstallerProjectRoot)pkg\sfx\Microsoft.NETCore.App\Microsoft.NETCore.App.Crossgen2.sfxproj" />
         <SharedFrameworkProjectToBuild Condition="'$(RuntimeFlavor)' == '$(PrimaryRuntimeFlavor)'" Include="$(InstallerProjectRoot)pkg\sfx\installers\dotnet-host.proj" />
         <SharedFrameworkProjectToBuild Condition="'$(RuntimeFlavor)' == '$(PrimaryRuntimeFlavor)'" Include="$(InstallerProjectRoot)pkg\sfx\installers\dotnet-hostfxr.proj" />
         <SharedFrameworkProjectToBuild Condition="'$(RuntimeFlavor)' == '$(PrimaryRuntimeFlavor)'" Include="$(InstallerProjectRoot)pkg\sfx\installers\dotnet-runtime-deps\*.proj" />
@@ -519,7 +519,7 @@
         <SharedFrameworkProjectToBuild Condition="'$(MonoCrossAOTTargetOS)' != ''" Include="$(InstallerProjectRoot)pkg\sfx\Microsoft.NETCore.App\monocrossaot.sfxproj" Pack="true" />
       </ItemGroup>
       <ItemGroup>
-        <ProjectToBuild Condition="'$(NativeAotSupported)' == 'true' and '$(RuntimeFlavor)' != 'Mono'" Include="$(InstallerProjectRoot)\pkg\projects\nativeaot-packages.proj" Category="packs" />
+        <ProjectToBuild Condition="'$(NativeAotSupported)' == 'true' and '$(RuntimeFlavor)' != 'Mono' and '$(PgoInstrument)' != 'true'" Include="$(InstallerProjectRoot)\pkg\projects\nativeaot-packages.proj" Category="packs" />
       </ItemGroup>
       <ItemGroup>
         <SharedFrameworkProjectToBuild Condition="'$(BuildMonoAOTCrossCompilerOnly)' != 'true'" Include="$(InstallerProjectRoot)pkg\sfx\Microsoft.NETCore.App\Microsoft.NETCore.App.Runtime.sfxproj" />