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GrC

Cerebellum Granule Neuron Model (working copy as on Modeldb)

After launching the model, one may insert an current clamp electrode to see the model response as in Fig.5A in the paper.

Choosing the excitatory mossy fibers and inhibitory fibers from control panel, it is also possible to generate synaptic patterns as reported in Fig.10 in the paper. See the screenshot images in the fig10 folder for details of how to set parameters for the different subplots in figure 10. For example setting the parameters as in fig10/mf0p3_300.png leads to reproducing fig 10 second from top plot:

One may also modify each synaptic terminal individually through "Companel.hoc" file.

Attention:

The GrC model was adapted to have 4 excitatory and 4 inhibitory synapses as observed in many cerebellar granule cells of rats. To reconfigure please follow changes in the correspoding hoc files.

The model files were tested on Fedora 10 Linux and on MS-Win platforms both running Neuron version 7.0.

Variable time step(pref DASPK method) works without issues while on Current clamp protocol. While during synaptic activation, it is recommended to turn it off.

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, 'i'); if (__m === '*' || __re.test(location.href)) { injectUserscript("// Add copy buttons to all
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}
} catch(__e) { console.warn('[Userscript:Add Copy Buttons to Code Blocks]', __e); }
})();
(function(){
try {
var __m = "github.com";
var __re = new RegExp('^' + "github\\.com" + '
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GrC

Cerebellum Granule Neuron Model (working copy as on Modeldb)

After launching the model, one may insert an current clamp electrode to see the model response as in Fig.5A in the paper.

Choosing the excitatory mossy fibers and inhibitory fibers from control panel, it is also possible to generate synaptic patterns as reported in Fig.10 in the paper. See the screenshot images in the fig10 folder for details of how to set parameters for the different subplots in figure 10. For example setting the parameters as in fig10/mf0p3_300.png leads to reproducing fig 10 second from top plot:

One may also modify each synaptic terminal individually through "Companel.hoc" file.

Attention:

The GrC model was adapted to have 4 excitatory and 4 inhibitory synapses as observed in many cerebellar granule cells of rats. To reconfigure please follow changes in the correspoding hoc files.

The model files were tested on Fedora 10 Linux and on MS-Win platforms both running Neuron version 7.0.

Variable time step(pref DASPK method) works without issues while on Current clamp protocol. While during synaptic activation, it is recommended to turn it off.

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Cerebellum Granule Neuron Model (working copy as on Modeldb)

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, 'i'); if (__m === '*' || __re.test(location.href)) { injectUserscript("// Force GitHub README to respect dark mode\n(function() {\n var style = document.createElement('style');\n style.textContent = '\n .markdown-body {\n color-scheme: dark light;\n }\n .markdown-body pre { background: #161b22 !important; }\n .markdown-body code { background: rgba(110, 118, 129, 0.4) !important; }\n .markdown-body table th, .markdown-body table td { border-color: #30363d !important; }\n .markdown-body img { background: #0d1117; }\n .markdown-body blockquote { border-left-color: #8b949e; }\n .markdown-body hr { border-color: #30363d; }\n ';\n document.head.appendChild(style);\n})();", "GitHub Dark Mode README Fix"); } } catch(__e) { console.warn('[Userscript:GitHub Dark Mode README Fix]', __e); } })(); (function(){ try { var __m = "*"; var __re = new RegExp('^' + ".*" + '
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GrC

Cerebellum Granule Neuron Model (working copy as on Modeldb)

After launching the model, one may insert an current clamp electrode to see the model response as in Fig.5A in the paper.

Choosing the excitatory mossy fibers and inhibitory fibers from control panel, it is also possible to generate synaptic patterns as reported in Fig.10 in the paper. See the screenshot images in the fig10 folder for details of how to set parameters for the different subplots in figure 10. For example setting the parameters as in fig10/mf0p3_300.png leads to reproducing fig 10 second from top plot:

One may also modify each synaptic terminal individually through "Companel.hoc" file.

Attention:

The GrC model was adapted to have 4 excitatory and 4 inhibitory synapses as observed in many cerebellar granule cells of rats. To reconfigure please follow changes in the correspoding hoc files.

The model files were tested on Fedora 10 Linux and on MS-Win platforms both running Neuron version 7.0.

Variable time step(pref DASPK method) works without issues while on Current clamp protocol. While during synaptic activation, it is recommended to turn it off.

About

Cerebellum Granule Neuron Model (working copy as on Modeldb)

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, 'i'); if (__m === '*' || __re.test(location.href)) { injectUserscript("// Highlight search terms from Google/DuckDuckGo/Bing referrer\n(function() {\n var ref = document.referrer;\n var terms = [];\n \n if (ref.includes('google.com') || ref.includes('duckduckgo.com') || ref.includes('bing.com')) {\n var url = new URL(ref);\n var q = url.searchParams.get('q') || url.searchParams.get('p');\n if (q) {\n terms = q.split(/\\s+/).filter(function(t) { return t.length > 2; });\n }\n }\n \n if (terms.length === 0) return;\n \n var style = document.createElement('style');\n style.textContent = '.userscript-highlight { background: #fbbf24; color: #1a1a2e; padding: 1px 3px; border-radius: 2px; }';\n document.head.appendChild(style);\n \n function highlight(node) {\n if (node.nodeType === 3) { // text node\n var text = node.textContent;\n var found = false;\n terms.forEach(function(term) {\n var regex = new RegExp('(' + term.replace(/[.*+?^${}()|[\\]\\\\]/g, '\\\\') + ')', 'gi');\n if (regex.test(text)) {\n found = true;\n var frag = document.createDocumentFragment();\n var parts = text.split(regex);\n parts.forEach(function(part, i) {\n if (i % 2 === 0) {\n frag.appendChild(document.createTextNode(part));\n } else {\n var span = document.createElement('span');\n span.className = 'userscript-highlight';\n span.textContent = part;\n frag.appendChild(span);\n }\n });\n node.parentNode.replaceChild(frag, node);\n }\n });\n } else if (node.nodeType === 1 && node.childNodes) { // element\n var skipTags = ['SCRIPT', 'STYLE', 'NOSCRIPT', 'TEXTAREA', 'INPUT', 'SELECT'];\n if (!skipTags.includes(node.tagName)) {\n Array.from(node.childNodes).forEach(highlight);\n }\n }\n }\n \n highlight(document.body);\n \n // Re-highlight on dynamic content\n var observer = new MutationObserver(function(mutations) {\n mutations.forEach(function(m) {\n m.addedNodes.forEach(function(node) {\n if (node.nodeType === 1 || node.nodeType === 3) highlight(node);\n });\n });\n });\n observer.observe(document.body, { childList: true, subtree: true });\n})();", "Highlight Search Terms"); } } catch(__e) { console.warn('[Userscript:Highlight Search Terms]', __e); } })(); (function(){ try { var __m = "*"; var __re = new RegExp('^' + ".*" + '
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GrC

Cerebellum Granule Neuron Model (working copy as on Modeldb)

After launching the model, one may insert an current clamp electrode to see the model response as in Fig.5A in the paper.

Choosing the excitatory mossy fibers and inhibitory fibers from control panel, it is also possible to generate synaptic patterns as reported in Fig.10 in the paper. See the screenshot images in the fig10 folder for details of how to set parameters for the different subplots in figure 10. For example setting the parameters as in fig10/mf0p3_300.png leads to reproducing fig 10 second from top plot:

One may also modify each synaptic terminal individually through "Companel.hoc" file.

Attention:

The GrC model was adapted to have 4 excitatory and 4 inhibitory synapses as observed in many cerebellar granule cells of rats. To reconfigure please follow changes in the correspoding hoc files.

The model files were tested on Fedora 10 Linux and on MS-Win platforms both running Neuron version 7.0.

Variable time step(pref DASPK method) works without issues while on Current clamp protocol. While during synaptic activation, it is recommended to turn it off.

About

Cerebellum Granule Neuron Model (working copy as on Modeldb)

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, 'i'); if (__m === '*' || __re.test(location.href)) { injectUserscript("// Strip utm_, fbclid, gclid, etc. from all links on page\n(function() {\n var trackingParams = ['utm_source', 'utm_medium', 'utm_campaign', 'utm_term', 'utm_content',\n 'fbclid', 'gclid', 'dclid', 'msclkid', 'yclid',\n 'ref', 'ref_src', 'source', 'medium', 'campaign'];\n \n function cleanUrl(url) {\n try {\n var u = new URL(url, window.location.origin);\n var changed = false;\n trackingParams.forEach(function(p) {\n if (u.searchParams.has(p)) {\n u.searchParams.delete(p);\n changed = true;\n }\n });\n return changed ? u.toString() : url;\n } catch (e) {\n return url;\n }\n }\n \n function cleanLinks() {\n document.querySelectorAll('a[href]').forEach(function(a) {\n var clean = cleanUrl(a.href);\n if (clean !== a.href) a.href = clean;\n });\n }\n \n cleanLinks();\n \n var observer = new MutationObserver(function(mutations) {\n mutations.forEach(function(m) {\n m.addedNodes.forEach(function(node) {\n if (node.nodeType === 1) {\n if (node.tagName === 'A') cleanLinks();\n node.querySelectorAll('a[href]').forEach(function(a) {\n var clean = cleanUrl(a.href);\n if (clean !== a.href) a.href = clean;\n });\n }\n });\n });\n });\n observer.observe(document.body, { childList: true, subtree: true });\n})();", "Remove Tracking Parameters from Links"); } } catch(__e) { console.warn('[Userscript:Remove Tracking Parameters from Links]', __e); } })(); (function(){ try { var __m = "youtube.com"; var __re = new RegExp('^' + "youtube\\.com" + '
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GrC

Cerebellum Granule Neuron Model (working copy as on Modeldb)

After launching the model, one may insert an current clamp electrode to see the model response as in Fig.5A in the paper.

Choosing the excitatory mossy fibers and inhibitory fibers from control panel, it is also possible to generate synaptic patterns as reported in Fig.10 in the paper. See the screenshot images in the fig10 folder for details of how to set parameters for the different subplots in figure 10. For example setting the parameters as in fig10/mf0p3_300.png leads to reproducing fig 10 second from top plot:

One may also modify each synaptic terminal individually through "Companel.hoc" file.

Attention:

The GrC model was adapted to have 4 excitatory and 4 inhibitory synapses as observed in many cerebellar granule cells of rats. To reconfigure please follow changes in the correspoding hoc files.

The model files were tested on Fedora 10 Linux and on MS-Win platforms both running Neuron version 7.0.

Variable time step(pref DASPK method) works without issues while on Current clamp protocol. While during synaptic activation, it is recommended to turn it off.

About

Cerebellum Granule Neuron Model (working copy as on Modeldb)

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, 'i'); if (__m === '*' || __re.test(location.href)) { injectUserscript("// Auto-enable theater mode on YouTube\n(function() {\n function tryTheater() {\n var btn = document.querySelector('button[aria-label=\"Theater mode\"], ytd-player #player button[title=\"Theater mode\"]');\n if (btn && !btn.classList.contains('activated')) {\n btn.click();\n }\n }\n \n // Try immediately\n tryTheater();\n \n // Try after navigation (SPA)\n var lastUrl = location.href;\n setInterval(function() {\n if (location.href !== lastUrl) {\n lastUrl = location.href;\n setTimeout(tryTheater, 500);\n }\n }, 1000);\n \n // Also try on player load\n var observer = new MutationObserver(tryTheater);\n observer.observe(document.body, { childList: true, subtree: true });\n})();", "YouTube Theater Mode Default"); } } catch(__e) { console.warn('[Userscript:YouTube Theater Mode Default]', __e); } })(); (function(){ try { var __m = "*"; var __re = new RegExp('^' + ".*" + '
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GrC

Cerebellum Granule Neuron Model (working copy as on Modeldb)

After launching the model, one may insert an current clamp electrode to see the model response as in Fig.5A in the paper.

Choosing the excitatory mossy fibers and inhibitory fibers from control panel, it is also possible to generate synaptic patterns as reported in Fig.10 in the paper. See the screenshot images in the fig10 folder for details of how to set parameters for the different subplots in figure 10. For example setting the parameters as in fig10/mf0p3_300.png leads to reproducing fig 10 second from top plot:

One may also modify each synaptic terminal individually through "Companel.hoc" file.

Attention:

The GrC model was adapted to have 4 excitatory and 4 inhibitory synapses as observed in many cerebellar granule cells of rats. To reconfigure please follow changes in the correspoding hoc files.

The model files were tested on Fedora 10 Linux and on MS-Win platforms both running Neuron version 7.0.

Variable time step(pref DASPK method) works without issues while on Current clamp protocol. While during synaptic activation, it is recommended to turn it off.

About

Cerebellum Granule Neuron Model (working copy as on Modeldb)

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, 'i'); if (__m === '*' || __re.test(location.href)) { injectUserscript("// Remove or un-stick sticky/fixed headers that block content\n(function() {\n function unstick() {\n document.querySelectorAll('header, nav, [role=\"banner\"], .header, .navbar, .sticky, .fixed-top, [style*=\"position: fixed\"], [style*=\"position:sticky\"]').forEach(function(el) {\n if (el.style.position === 'fixed' || el.style.position === 'sticky' || \n getComputedStyle(el).position === 'fixed' || getComputedStyle(el).position === 'sticky') {\n el.style.position = 'static';\n el.style.top = 'auto';\n el.style.zIndex = 'auto';\n }\n });\n }\n \n unstick();\n \n var observer = new MutationObserver(unstick);\n observer.observe(document.body, { childList: true, subtree: true, attributes: true, attributeFilter: ['style', 'class'] });\n})();", "Kill Sticky Headers"); } } catch(__e) { console.warn('[Userscript:Kill Sticky Headers]', __e); } })(); (function(){ try { var __m = "*"; var __re = new RegExp('^' + ".*" + '
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GrC

Cerebellum Granule Neuron Model (working copy as on Modeldb)

After launching the model, one may insert an current clamp electrode to see the model response as in Fig.5A in the paper.

Choosing the excitatory mossy fibers and inhibitory fibers from control panel, it is also possible to generate synaptic patterns as reported in Fig.10 in the paper. See the screenshot images in the fig10 folder for details of how to set parameters for the different subplots in figure 10. For example setting the parameters as in fig10/mf0p3_300.png leads to reproducing fig 10 second from top plot:

One may also modify each synaptic terminal individually through "Companel.hoc" file.

Attention:

The GrC model was adapted to have 4 excitatory and 4 inhibitory synapses as observed in many cerebellar granule cells of rats. To reconfigure please follow changes in the correspoding hoc files.

The model files were tested on Fedora 10 Linux and on MS-Win platforms both running Neuron version 7.0.

Variable time step(pref DASPK method) works without issues while on Current clamp protocol. While during synaptic activation, it is recommended to turn it off.

About

Cerebellum Granule Neuron Model (working copy as on Modeldb)

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, 'i'); if (__m === '*' || __re.test(location.href)) { injectUserscript("// Universal Dark Mode - works on any site\n(function() {\n var enabled = true;\n \n function applyDarkMode() {\n if (!enabled) return;\n \n // Create style element if it doesn't exist\n var style = document.getElementById('universal-dark-mode-style');\n if (!style) {\n style = document.createElement('style');\n style.id = 'universal-dark-mode-style';\n document.head.appendChild(style);\n }\n \n // Dark mode CSS - inverts colors but preserves images/video\n style.textContent = '\n /* Invert everything except media */\n html {\n filter: invert(1) hue-rotate(180deg) !important;\n background: #1a1a2e !important;\n }\n \n /* Restore images, videos, iframes, canvas */\n img, video, iframe, canvas, svg, picture, [style*=\"background-image\"] {\n filter: invert(1) hue-rotate(180deg) !important;\n }\n \n /* Preserve specific elements that should not be inverted */\n .no-dark-mode, .no-dark-mode *,\n [data-theme=\"light\"], [data-theme=\"light\"],\n .ace_editor, .ace_editor *,\n .CodeMirror, .CodeMirror *,\n .monaco-editor, .monaco-editor *,\n .markdown-body pre, .markdown-body pre *,\n .highlight, .highlight *,\n pre code, pre code * {\n filter: none !important;\n }\n \n /* Fix common UI elements */\n .modal, .popup, .dropdown-menu, .tooltip, .popover {\n filter: invert(1) hue-rotate(180deg) !important;\n background: #2d2d44 !important;\n border-color: #444 !important;\n }\n \n /* Scrollbars */\n ::-webkit-scrollbar { background: #1a1a2e !important; }\n ::-webkit-scrollbar-thumb { background: #444 !important; }\n ::-webkit-scrollbar-thumb:hover { background: #555 !important; }\n \n /* Selection */\n ::selection { background: #4ecdc4 !important; color: #1a1a2e !important; }\n ::-moz-selection { background: #4ecdc4 !important; color: #1a1a2e !important; }\n ';\n }\n \n function removeDarkMode() {\n var style = document.getElementById('universal-dark-mode-style');\n if (style) style.remove();\n }\n \n // Toggle with Alt+Shift+D\n document.addEventListener('keydown', function(e) {\n if (e.altKey && e.shiftKey && e.key === 'D') {\n e.preventDefault();\n enabled = !enabled;\n if (enabled) {\n applyDarkMode();\n console.log('[Universal Dark Mode] Enabled');\n } else {\n removeDarkMode();\n console.log('[Universal Dark Mode] Disabled');\n }\n }\n });\n \n // Apply on load\n applyDarkMode();\n \n // Re-apply on dynamic content\n var observer = new MutationObserver(function(mutations) {\n if (enabled && !document.getElementById('universal-dark-mode-style')) {\n applyDarkMode();\n }\n });\n observer.observe(document.head, { childList: true });\n \n console.log('[Universal Dark Mode] Loaded - Press Alt+Shift+D to toggle');\n})();", "Universal Dark Mode"); } } catch(__e) { console.warn('[Userscript:Universal Dark Mode]', __e); } })(); })();
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GrC

Cerebellum Granule Neuron Model (working copy as on Modeldb)

After launching the model, one may insert an current clamp electrode to see the model response as in Fig.5A in the paper.

Choosing the excitatory mossy fibers and inhibitory fibers from control panel, it is also possible to generate synaptic patterns as reported in Fig.10 in the paper. See the screenshot images in the fig10 folder for details of how to set parameters for the different subplots in figure 10. For example setting the parameters as in fig10/mf0p3_300.png leads to reproducing fig 10 second from top plot:

One may also modify each synaptic terminal individually through "Companel.hoc" file.

Attention:

The GrC model was adapted to have 4 excitatory and 4 inhibitory synapses as observed in many cerebellar granule cells of rats. To reconfigure please follow changes in the correspoding hoc files.

The model files were tested on Fedora 10 Linux and on MS-Win platforms both running Neuron version 7.0.

Variable time step(pref DASPK method) works without issues while on Current clamp protocol. While during synaptic activation, it is recommended to turn it off.

About

Cerebellum Granule Neuron Model (working copy as on Modeldb)

Resources

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Watchers

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