Open-source personal genomics — upload your VCF, get longevity insights, disease risks, 5,000+ polygenic risk scores, and epigenetic clocks in minutes. Runs entirely on your machine.
| Repo | What it does |
|---|---|
| just-dna-lite | The platform: Reflex web UI, annotation modules, PRS, AI Module Creator |
| just-prs | Pure-Python PRS engine — 5,000+ PGS Catalog scores, validated against PLINK2 (r = 1.0) |
| just-biomarkers | 44 epigenetic clocks from methylation data (Horvath, PhenoAge, DunedinPACE, …) |
# Try just-dna-lite in three commands
git clone https://github.com/dna-seq/just-dna-lite.git &&cd just-dna-lite
uv sync && uv run startOther repositories
Pipelines & tools
- dna-seq – WDL sequencing pipelines
- prepare-annotations – Ensembl annotation data pipeline
- neural_networks – Deep learning for genetic phenotype prediction
Legacy (first-generation OakVar modules)
just-dna.life · Telegram · arXiv preprint
Supported by ROGEN, HEALES, IBIMA, Systems Biology of Aging Group. Core developers also contribute to Longevity Genie.