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Likelihood Approach for Mediation Analysis in Case-Control Studies

Test for association between a set of rare (and common) variants and continuous/dichotomous phenotypes using kernel machine methods

Software for association analysis of triads and unrelated subjects

Chaplin is software for identifying specific haplotypes or haplotype features that are associated with disease using genotype data from a case-control study. The program utilizes statistical methodology initially developed in Epstein and Satten (2003) and explored further in Satten and Epstein (2004). Chaplin is a Win32 application written in FO…

This R package is a modified version of the 'BiasedUrn' package developed by Agner Fog; the original package can be found on the CRAN site. We created this modified package to facilitate permutation-based testing of disease-exposure association in case-control studies that accounts for potential confounders. In particular, such permutation-based…

We developed an R function to allow users to perform robust joint testing of SNP and SNP-environment interaction within the PLINK software toolset for whole genome association analysis. The software implements statistical methodology published in Almli et al. (2014).