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ncborcherding/README.md

Hi, I'm Nick Borcherding

Assistant Professor | Computational Immunologist | Tool Builder

Washington University · Department of Pathology & Immunology

WebsiteGoogle ScholarLab


About Me

I work at the intersection of computational biology and immunology, developing tools and methods to decode immune responses from high-dimensional data.

  • MD/PhD — University of Iowa (Medical Scientist Training Program)
  • Residency & Postdoc — Washington University PSTP (co-mentored by Jon Brestoff & David DeNardo)
  • Fellowship - Histocompatibility and Immunogenetics
  • Focus — Innate cellular barcodes (mitochondrial genomes, immune receptor sequences) for tracking immune responses and predicting clinical outcomes

Software

I build R/Bioconductor packages for single-cell immune analysis:

scRepertoire
TCR/BCR repertoire analysis
escape
Gene set enrichment
Trex
TCR deep learning
Ibex
BCR deep learning
immApex
Immune receptor featurization

In development:immReferent · immLynx · immGLIPH · deepMatchR · bHIVE


GitHub Stats

Nick's GitHub stats


Get in Touch

  • Bug reports or feature requests? Open an issue on the relevant repo
  • Collaboration inquiries? Reach out via my website
  • Publications? PDFs available at borch.dev
Building tools to decode the immune system 🧬

Buy Me A Coffee

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  1. BorchLab/scRepertoireBorchLab/scRepertoirePublic

    A toolkit for single-cell immune profiling

    R 374 72

  2. BorchLab/escapeBorchLab/escapePublic

    Easy single cell analysis platform for enrichment

    R 229 23

  3. utilityutilityPublic

    Collection of Tumor-Infiltrating Lymphocyte Single-Cell Experiments with TCR

    R 115 8

  4. BorchLab/TrexBorchLab/TrexPublic

    Using TCR and expression for sequence embedding

    R 63 6

  5. BorchLab/IbexBorchLab/IbexPublic

    Using BCR and expression for sequence embedding

    R 27 4

  6. BorchLab/immApexBorchLab/immApexPublic

    Tools for Adaptive Immune Receptor Sequence-Based Machine and Deep Learning

    R 14 3