Quantitative Translational Scientist | PK/PD • Multi-Omics • Spatial Biology • ML • Shiny Tools
- QSPplus
- Boston
- https://tjmb03.github.io/QSPplus/
- @QSPplus
Pinned Loading
- CAR-T-BCMA-QSP
CAR-T-BCMA-QSP PublicMechanistic QSP of BCMA CAR-T in multiple myeloma: antigen-escape dynamics, cross-validated R↔Julia.
- ODEs-QSP
ODEs-QSP PublicMechanistic ODE QSP models: 13-state GBM tumor-immune + 14-state complement-neurodegeneration. MATLAB SimBiology + Python.
HTML
- bispecific-FIH-dosability
bispecific-FIH-dosability PublicMechanistic first-in-human dosability screen for tumor-targeted bispecific antibodies — go/no-go and dosability-margin ranking computed from binding parameters, before any dose exists.
Python
- OPT-CDISC-pipeline
OPT-CDISC-pipeline PublicIndependent CDISC mapping of a real published RCT — SDTM → ADaM → TLG in R, built from a wide non-CDISC source extract. Every mapping decision documented; 38 validation checks against raw. sdtm.oak…
R
- GLP1-oral-PBPK
GLP1-oral-PBPK PublicHTML
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