Standardized parameterization of sinoatrial node myocyte action potentials
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Updated
Aug 24, 2021 - Python
Standardized parameterization of sinoatrial node myocyte action potentials
Source code and data used in the article "Importance of modelling hERG binding in predicting drug-induced action potential prolongations for drug safety assessment" (Farm et al. Frontiers in Pharmacology, 2023)
Code associated with a publication on the action potential model parameter representing missing charge
A Python simulation of action potential generation using the Hodgkin-Huxley model, capturing voltage-dependent ion channel dynamics and membrane potential changes in response to current injection.
A curated, citation-backed cardiac channel-block dataset and human ventricular action-potential simulation pipeline that quantifies how input data variability propagates into proarrhythmia risk distributions and classification stability, rather than issuing rigid safety verdicts.
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