ancova

Compound-agnostic Design of Experiments (DOE) & Response Surface Methodology toolkit in Python. Config-driven factor/response setup with covariate (ANCOVA) and blocking support, Box-Behnken/CCD/factorial designs, ANOVA, desirability optimization, robust operating windows, publication-ready figures, and automated PDF reports. CLI + library

Endotype-aware GWAS pipeline using ANCOVA to detect subtype-specific genetic variants. Discovery in CAMP and validation in GACRS childhood asthma cohorts.