esm3

EvolutionaryScale — independent third-party profile of a public API surface, by API Evangelist. EvolutionaryScale is a New York-based biology foundation model lab spun out of Meta AI's ESM team that develops AI to deepen scientific understanding of biology. Its flagship ESM3 model is a multimodal generative protein language model that reasons joint

Propeptide cleavage site prediction from frozen protein language model embeddings, comparing ESM-2, ESM3, ProstT5 and one-hot on one task. Built on DeepPeptide.

In silico evolution of antimicrobial peptides: ESM3 folding, MACREL activity scoring and PFES structural terms, with a three-origin by two-objective ablation.

This repository integrates ESM, EvolutionaryScale's protein language models, with the ExoStack platform to enable scalable AI-driven protein analysis, inference, and deployment.