DMS-PrefRank: ProteinGym PG_v1.3 preference reranking benchmark for protein variant recommendation.
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Updated
Jun 16, 2026 - Python
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proteingym
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Zero-shot missense variant effect prediction with ESM-2. Full mutational landscape, Mol* 3D structure coloured by predicted impact, DSSP features, and ClinVar/AlphaMissense annotations. Benchmarked on ProteinGym (mean Spearman 0.447).
machine-learningbioinformaticsstructural-biologynextjscomputational-biologypytorchvariant-effect-predictionfastapialphafoldprotein-language-modelmolstaresm2proteingym
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Updated
Aug 14, 2026 - Python
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