Miniprotein and antibody design pipeline for ESMFold2
-
Updated
Sep 13, 2026 - Python
Miniprotein and antibody design pipeline for ESMFold2
Code for NeurIPS 2024 paper "A SARS-CoV-2 Interaction Dataset and VHH Sequence Corpus for Antibody Language Models"
Small, fast, fully differentiable antibody Fv structure predictor in JAX. ~0.76M parameters, matches IgFold on CDR-H3, folds an Fv in ~0.8s on CPU.
Build a structural nanobody library from the PDB: mine RCSB for nanobody/VHH entries, split nanobody and antigen chains, renumber and superpose in headless PyMOL
For NBsTem Webserver
To associate your repository with the vhh topic, visit your repo's landing page and select "manage topics."