opentargets

Python client for the Open Targets REST API at targetvalidation.org

MCP server for Open Targets data

A python package to explore pathways, diseases and drugs associated to a list of targets (genes, proteins, etc)

Code for the data processing pipeline

Agent execution layer for biology workflows: batch gene scanning, tumor cohort briefing, target discovery — with structured outputs, resume, and pipeline-ready artifacts

Connecting AI to biomedical data

AI Agent wrappers for Life Sciences APIs (Open Targets, ChEMBL, UniProt). Accelerating drug discovery with Model Context Protocol (MCP) and FastMCP.

Assess the evolution over time of evidence supporting disease-target associations in the Open Targets Platform.

High-level feature tracker for all of Open Targets

Multi-source drug-target due-diligence: ranked gene list → per-gene dossier across UniProt, OpenTargets, PubMed + cross-lineage DE scan + composite re-ranking. Claude Code / OpenClaw / SkillsMP skill.

A comprehensive bioinformatics pipeline for downloading and analyzing genes associated with specific phenotypes from multiple biological databases. This package provides both R scripts for gene retrieval and Python analysis tools for downstream analysis.

💊 MediPharma — AI-driven drug discovery. ChEMBL 2.4M compounds, OpenTargets, ADMET prediction.

A GNN-based platform for predicting novel drug-target interactions to accelerate R&D.

A reproducible source-aware pipeline for integrating, harmonising, deduplicating, and analysing drug–disease relationships from 11 public biomedical databases, with processed data available on Zenodo.

This repository contains a fully reproducible pipeline for prioritising candidate genes and pathways from GWAS summary statistics using integrative pGWAS functional annotation to identify the most compelling targets for asthma

Agent-ready CLI for Open Targets data

kubernetes template files for open target services

Open Targets Platform REST API

Unofficial community-maintained Python client for the Open Targets Platform GraphQL API

An agentic AI pipeline for annotating genetic variants, linking them to disease evidence, and generating structured interpretation reports using biomedical APIs and LLM reasoning.