Comprehensive design of CRISPR gRNAs for nucleases and base editors
On-Target and Off-Target Scoring Algorithms for CRISPR gRNAs
A multi-source ensemble predictor for prioritizing sgRNAs in CRISPR/Cas9 protein knockouts
Visualization of CRISPR guide RNAs (gRNAs)
Useful human and mouse data for the crisprVerse ecosystem
Bowtie-based alignment of CRISPR gRNA spacer sequences
ALLEGRO is a synthetic biology tool that designs minimal, high activity CRISPR-Cas sgRNA libraries
Pre-trained models for the crisprScore package
BWA-based alignment of CRISPR gRNA spacer sequences
MutCrisper: A Toolkit for Optimized gRNA Design in Base Editing Technology
Distribution-Free Uncertainty Quantification, Multi-Objective Coverage Guarantees, and Conformal Selection for Generative Genomic Design.
Script used to cdesign sgRNA sequences based on desired input parameters comparing different web-based tools
CRIBAR: a fast and flexible sgRNA design tool for CRISPR-based imaging
sg5 sgRNA Designer is a command-line tool for designing CRISPR sgRNAs targeting Drosophila melanogaster genes using the SpCas9/NGG system. Fetches gene sequences directly from the Ensembl REST API, scans both strands for NGG PAM sites, scores each candidate guide, and outputs a ranked list.
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